Integrins control motile strategy through a Rho–cofilin pathway
During wound healing, angiogenesis, and tumor invasion, cells often change their expression profiles of fibronectin-binding integrins. Here, we show that β1 integrins promote random migration, whereas β3 integrins promote persistent migration in the same epithelial cell background. Adhesion to fibro...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171933/ |