Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

Autophagy is a membrane-trafficking mechanism that delivers cytoplasmic constituents into the lysosome/vacuole for bulk protein degradation. This mechanism is involved in the preservation of nutrients under starvation condition as well as the normal turnover of cytoplasmic component. Aberrant autoph...

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Bibliographic Details
Main Authors: Komatsu, Masaaki, Waguri, Satoshi, Ueno, Takashi, Iwata, Junichi, Murata, Shigeo, Tanida, Isei, Ezaki, Junji, Mizushima, Noboru, Ohsumi, Yoshinori, Uchiyama, Yasuo, Kominami, Eiki, Tanaka, Keiji, Chiba, Tomoki
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171928/