Temporal separation of replication and recombination requires the intra-S checkpoint

In response to DNA damage and replication pausing, eukaryotes activate checkpoint pathways that prevent genomic instability by coordinating cell cycle progression with DNA repair. The intra-S-phase checkpoint has been proposed to protect stalled replication forks from pathological rearrangements tha...

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Bibliographic Details
Main Authors: Meister, Peter, Taddei, Angela, Vernis, Laurence, Poidevin, Mickaël, Gasser, Susan M., Baldacci, Giuseppe
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171758/