X chromosome choice occurs independently of asynchronous replication timing
In mammals, dosage compensation is achieved by X chromosome inactivation in female cells. Xist is required and sufficient for X inactivation, and Xist gene deletions result in completely skewed X inactivation. In this work, we analyzed skewing of X inactivation in mice with an Xist deletion encompas...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171734/ |