The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: Identification of the nuclear pore complex as a potential target of the JNK pathway

c-Jun is induced in many neuronal death paradigms. A critical step in c-Jun regulation involves phosphorylation of Ser63/Ser73 located in the NH2-terminal transactivation domain. To determine the importance of this phosphorylation for neuronal apoptosis, we analyzed the sympathetic neurons of mice c...

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Bibliographic Details
Main Authors: Besirli, Cagri G., Wagner, Erwin F., Johnson, Eugene M.
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171472/