Regulation of Sar1 NH2 terminus by GTP binding and hydrolysis promotes membrane deformation to control COPII vesicle fission
The mechanisms by which the coat complex II (COPII) coat mediates membrane deformation and vesicle fission are unknown. Sar1 is a structural component of the membrane-binding inner layer of COPII (Bi, X., R.A. Corpina, and J. Goldberg. 2002. Nature. 419:271–277). Using model liposomes we found that...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171319/ |