Rootletin forms centriole-associated filaments and functions in centrosome cohesion

After duplication of the centriole pair during S phase, the centrosome functions as a single microtubule-organizing center until the onset of mitosis, when the duplicated centrosomes separate for bipolar spindle formation. The mechanisms regulating centrosome cohesion and separation during the cell...

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Bibliographic Details
Main Authors: Bahe, Susanne, Stierhof, York-Dieter, Wilkinson, Christopher J., Leiss, Florian, Nigg, Erich A.
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171225/