Integrin-Mediated Adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1

Integrin-mediated adhesion to the extracellular matrix permits efficient growth factor-mediated activation of extracellular signal–regulated kinases (ERKs). Points of regulation have been localized to the level of receptor phosphorylation or to activation of the downstream components, Raf and MEK (m...

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Bibliographic Details
Main Authors: Aplin, Andrew E., Stewart, Sheryl A., Assoian, Richard K., Juliano, R.L.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169466/