Identities of Sequestered Proteins in Aggregates from Cells with Induced Polyglutamine Expression

Proteins with expanded polyglutamine (polyQ) tracts have been linked to neurodegenerative diseases. One common characteristic of expanded-polyQ expression is the formation of intracellular aggregates (IAs). IAs purified from polyQ-expressing cells were dissociated and studied by protein blot assay a...

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Bibliographic Details
Main Authors: Suhr, Steven T., Senut, Marie-Claude, Whitelegge, Julian P., Faull, Kym F., Cuizon, Denise B., Gage, Fred H.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169460/