Activation of the Cdc42 Effector N-Wasp by the Shigella flexneri Icsa Protein Promotes Actin Nucleation by Arp2/3 Complex and Bacterial Actin-Based Motility

Activation of the Cdc42 Effector N-Wasp by the Shigella flexneri Icsa Protein Promotes Actin Nucleation by Arp2/3 Complex and Bacterial Actin-Based Motility

To propel itself in infected cells, the pathogen Shigella flexneri subverts the Cdc42-controlled machinery responsible for actin assembly during filopodia formation. Using a combination of bacterial motility assays in platelet extracts with Escherichia coli expressing the Shigella IcsA protein and i...

Full description

Bibliographic Details
Main Authors: Egile, Coumaran, Loisel, Thomas P., Laurent, Valérie, Li, Rong, Pantaloni, Dominique, Sansonetti, Philippe J., Carlier, Marie-France
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156126/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156126/

Similar Items