Distinct Populations of HCN Pacemaker Channels Produce Voltage-dependent and Voltage-independent Currents

Hyperpolarization-activated HCN pacemaker channels are critical for the generation of spontaneous activity and the regulation of excitability in the heart and in many types of neurons. These channels produce both a voltage-dependent current (Ih) and a voltage-independent current (Iinst or VIC). In t...

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Bibliographic Details
Main Authors: Proenza, Catherine, Yellen, Gary
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151495/