Methylation of CpG island is not a ubiquitous mechanism for the loss of oestrogen receptor in breast cancer cells.
Methylation has been shown to play an important role in the down-regulation of oestrogen receptors (ER) in breast cancer cells. One critical question that remains unclear is whether methylation can account for the loss of ER expression in cells derived from an ER-positive cell line. This laboratory...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
1998
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151219/ |