Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix–induced apoptosis

Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix–induced apoptosis

Little is known about the fate of normal human mammary epithelial cells (HMECs) that lose p53 function in the context of extracellular matrix (ECM)–derived growth and polarity signals. Retrovirally mediated expression of human papillomavirus type 16 (HPV-16) E6 and antisense oligodeoxynucleotides (O...

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Bibliographic Details
Main Authors: Seewaldt, Victoria L., Mrózek, Krzysztof, Sigle, Randy, Dietze, Eric C., Heine, Kevin, Hockenbery, David M., Hobbs, Katherine B., Caldwell, L. Elizabeth
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150841/

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