Cyclophosphamide, methotrexate and infusional 5-fluorouracil (infusional CMF) in metastatic breast cancer.
Bolus 5-fluorouracil (5-FU) is a phase-specific drug with a short plasma half-life that is used in combination with bolus cyclophosphamide and methotrexate in the treatment of breast cancer. The efficacy of 5-FU can be improved by continuous intravenous infusion using portable infusion pumps (infusi...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
1998
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150339/ |