Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis.

Human AP endonuclease (HAP1) plays a major role in the repair of apurinic/apyrimidinic (AP) sites in cellular DNA. We used immunohistochemistry to examine the expression of HAP1 in normal breast and in 102 primary breast carcinomas. In normal breast epithelium, HAP1 had a uniformly nuclear localizat...

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Bibliographic Details
Main Authors: Kakolyris, S., Kaklamanis, L., Engels, K., Fox, S. B., Taylor, M., Hickson, I. D., Gatter, K. C., Harris, A. L.
Format: Online
Language:English
Published: Nature Publishing Group 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150123/