Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells.
To investigate the possible dependence of 5-fluorouracil (5FU) uptake in tumours on the intra- (pHi) and extracellular (pHe) pH, a pH gradient (deltapH) was imposed across the plasma membrane of ascites tumour cells in vitro, similar to that known to occur in some solid tumours in vivo, by incubatio...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
1998
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150086/ |