Kinetic Pathway of Pyrophosphorolysis by a Retrotransposon Reverse Transcriptase
DNA and RNA polymerases use a common phosphoryl transfer mechanism for base addition that requires two or three acidic amino acid residues at their active sites. We previously showed, for the reverse transcriptase (RT) encoded by the yeast retrotransposon Ty1, that one of the three conserved active...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Public Library of Science
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148107/ |