THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH

In nutrient broth at 30 to 32°C., the cycle of virus growth (following adsorption) in lag phase cells of B. mycoides N included a period of intracellular multiplication, ranging from 0.8 to 1.3 hours, succeeded by a sharp rise in the free phage titer and then by a slower rise or a plateau in the ex...

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Main Authors: Baer, B. S., Krueger, A. P.
Format: Online
Language:English
Published: The Rockefeller University Press 1952
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147347/
id pubmed-2147347
recordtype oai_dc
spelling pubmed-21473472008-04-23 THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH Baer, B. S. Krueger, A. P. Article In nutrient broth at 30 to 32°C., the cycle of virus growth (following adsorption) in lag phase cells of B. mycoides N included a period of intracellular multiplication, ranging from 0.8 to 1.3 hours, succeeded by a sharp rise in the free phage titer and then by a slower rise or a plateau in the extracellular phage content. The yield of virus per infected cell at 30°C., as determined by a modified Burnet dilution technique, was about 76 plaque-forming particles. During the latent period, multiply infected cells showed no change in numbers. Coinciding with phage release, incomplete clearing occurred. The unlysed, remaining cells multiplied and the turbidity rose again. These survivors and their progeny were lysogenic. The Rockefeller University Press 1952-09-20 /pmc/articles/PMC2147347/ /pubmed/12981236 Text en Copyright © Copyright, 1952, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Baer, B. S.
Krueger, A. P.
spellingShingle Baer, B. S.
Krueger, A. P.
THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH
author_facet Baer, B. S.
Krueger, A. P.
author_sort Baer, B. S.
title THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH
title_short THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH
title_full THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH
title_fullStr THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH
title_full_unstemmed THE B. MYCOIDES N HOST-VIRUS SYSTEM : II. INTERRELATION OF PHAGE GROWTH, BACTERIAL MULTIPLICATION, AND LYSIS IN INFECTIONS OF THE INDICATOR STRAIN OF B. MYCOIDES N WITH PHAGE N IN NUTRIENT BROTH
title_sort b. mycoides n host-virus system : ii. interrelation of phage growth, bacterial multiplication, and lysis in infections of the indicator strain of b. mycoides n with phage n in nutrient broth
description In nutrient broth at 30 to 32°C., the cycle of virus growth (following adsorption) in lag phase cells of B. mycoides N included a period of intracellular multiplication, ranging from 0.8 to 1.3 hours, succeeded by a sharp rise in the free phage titer and then by a slower rise or a plateau in the extracellular phage content. The yield of virus per infected cell at 30°C., as determined by a modified Burnet dilution technique, was about 76 plaque-forming particles. During the latent period, multiply infected cells showed no change in numbers. Coinciding with phage release, incomplete clearing occurred. The unlysed, remaining cells multiplied and the turbidity rose again. These survivors and their progeny were lysogenic.
publisher The Rockefeller University Press
publishDate 1952
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147347/
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