BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE
1. The biologic experiments with the links of the methane series—n-pentane, n-hexane, n-heptane, n-octane, i-octane, and pentene—gave these qualitative results: (a) The higher the number of CH2 groups, the longer the chain, the longer the average lifetime of the animal. (b) The ramified chain does...
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| Format: | Online |
| Language: | English |
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The Rockefeller University Press
1950
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147241/ |
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pubmed-2147241 |
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oai_dc |
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pubmed-21472412008-04-23 BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE Ettisch, G. Article 1. The biologic experiments with the links of the methane series—n-pentane, n-hexane, n-heptane, n-octane, i-octane, and pentene—gave these qualitative results: (a) The higher the number of CH2 groups, the longer the chain, the longer the average lifetime of the animal. (b) The ramified chain does not appear to act differently from the saturated straight chain with the same number of C atoms. (c) One double bond within the chain shortens the lifetime to a considerable degree. 2. The quantitative discussion shows that the lifetimes depend exponentially on the molecular weight. 3. Qualitatively the hypothesis is supported that with rising molecular weight the concentration of CH2 groups within the animal diminishes according to the vapor pressure or the thermodynamic potential. However, lifetime and these physical properties obey different functions. 4. These physical properties are of high biologic importance. But they are not sufficient to explain the biologic effects quantitatively. The Rockefeller University Press 1950-09-20 /pmc/articles/PMC2147241/ /pubmed/14778977 Text en Copyright © Copyright, 1950, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Ettisch, G. |
| spellingShingle |
Ettisch, G. BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE |
| author_facet |
Ettisch, G. |
| author_sort |
Ettisch, G. |
| title |
BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE |
| title_short |
BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE |
| title_full |
BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE |
| title_fullStr |
BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE |
| title_full_unstemmed |
BIOLOGIC SIGNIFICANCE OF THE STRUCTURE OF HYDROCARBONS : I. CHAIN STRUCTURE |
| title_sort |
biologic significance of the structure of hydrocarbons : i. chain structure |
| description |
1. The biologic experiments with the links of the methane series—n-pentane, n-hexane, n-heptane, n-octane, i-octane, and pentene—gave these qualitative results: (a) The higher the number of CH2 groups, the longer the chain, the longer the average lifetime of the animal. (b) The ramified chain does not appear to act differently from the saturated straight chain with the same number of C atoms. (c) One double bond within the chain shortens the lifetime to a considerable degree. 2. The quantitative discussion shows that the lifetimes depend exponentially on the molecular weight. 3. Qualitatively the hypothesis is supported that with rising molecular weight the concentration of CH2 groups within the animal diminishes according to the vapor pressure or the thermodynamic potential. However, lifetime and these physical properties obey different functions. 4. These physical properties are of high biologic importance. But they are not sufficient to explain the biologic effects quantitatively. |
| publisher |
The Rockefeller University Press |
| publishDate |
1950 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147241/ |
| _version_ |
1611423259116437504 |