The p75 Neurotrophin Receptor Mediates Neuronal Apoptosis and Is Essential for Naturally Occurring Sympathetic Neuron Death

Abstract. To determine whether the p75 neurotrophin receptor (p75NTR) plays a role in naturally occurring neuronal death, we examined neonatal sympathetic neurons that express both the TrkA tyrosine kinase receptor and p75NTR. When sympathetic neuron survival is maintained with low quantities of NGF...

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Bibliographic Details
Main Authors: Bamji, Shernaz X., Majdan, Marta, Pozniak, Christine D., Belliveau, Daniel J., Aloyz, Raquel, Kohn, Judi, Causing, Carrie G., Miller, Freda D.
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141754/