THE AUTODESTRUCTION OF PEPSIN IN RELATION TO ITS IONIZATION

1. Evidence is presented that pepsin is a univalent acid with a value for pK of 6.85 (or a base, with pK 7.39). 2. The autodestruction of the pepsin is shown to be dependent in part upon an instantaneous irreversible change occurring in the ionized form of the enzyme (if it be an acid) or in the un...

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Bibliographic Details
Main Authors: Goulding, Arthur M., Borsook, Henry, Wasteneys, Hardolph
Format: Online
Language:English
Published: The Rockefeller University Press 1927
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140918/