Movement of Bax from the Cytosol to Mitochondria during Apoptosis

Bax, a member of the Bcl-2 protein family, accelerates apoptosis by an unknown mechanism. Bax has been recently reported to be an integral membrane protein associated with organelles or bound to organelles by Bcl-2 or a soluble protein found in the cytosol. To explore Bcl-2 family member localizatio...

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Bibliographic Details
Main Authors: Wolter, Keith G., Hsu, Yi-Te, Smith, Carolyn L., Nechushtan, Amotz, Xi, Xu-Guang, Youle, Richard J.
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140220/