Plasmodium vivax Invasion of Human Erythrocytes Inhibited by Antibodies Directed against the Duffy Binding Protein

Christopher King and colleagues found that both rabbit and human antibodies inhibited binding of rPvDBPII to the Duffy antigen N-terminal region and to Duffy-positive human erythrocytes, suggesting that a PvDBP-based vaccine may reduce blood stage Plasmodium vivax infection.

Bibliographic Details
Main Authors: Grimberg, Brian T, Udomsangpetch, Rachanee, Xainli, Jia, McHenry, Amy, Panichakul, Tasanee, Sattabongkot, Jetsumon, Cui, Liwang, Bockarie, Moses, Chitnis, Chetan, Adams, John, Zimmerman, Peter A, King, Christopher L
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140086/