THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES
Outer thymic cortical large lymphocytes were labeled by transcapsular administration of tritiated thymidine. By 2–4 days after labeling, small and medium labeled lymphocyte descendants were found throughout the cortex and in the medulla. The labeled cortical lymphocytes undergo pycnosis after paren...
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| Format: | Online |
| Language: | English |
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The Rockefeller University Press
1973
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139480/ |
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pubmed-2139480 |
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oai_dc |
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pubmed-21394802008-04-17 THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES Weissman, Irving L. Article Outer thymic cortical large lymphocytes were labeled by transcapsular administration of tritiated thymidine. By 2–4 days after labeling, small and medium labeled lymphocyte descendants were found throughout the cortex and in the medulla. The labeled cortical lymphocytes undergo pycnosis after parenteral administration of hydrocortisone 24 h previously, but their (labeled) medullary descendants do not. In addition, parenteral administration of hydrocortisone at the time of surface labeling results in the absence of the appearance of labeled medullary descendants. The Rockefeller University Press 1973-01-31 /pmc/articles/PMC2139480/ /pubmed/4539848 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Weissman, Irving L. |
| spellingShingle |
Weissman, Irving L. THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES |
| author_facet |
Weissman, Irving L. |
| author_sort |
Weissman, Irving L. |
| title |
THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES |
| title_short |
THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES |
| title_full |
THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES |
| title_fullStr |
THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES |
| title_full_unstemmed |
THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES |
| title_sort |
thymus cell maturation : studies on the origin of cortisone-resistant thymic lymphocytes |
| description |
Outer thymic cortical large lymphocytes were labeled by transcapsular administration of tritiated thymidine. By 2–4 days after labeling, small and medium labeled lymphocyte descendants were found throughout the cortex and in the medulla. The labeled cortical lymphocytes undergo pycnosis after parenteral administration of hydrocortisone 24 h previously, but their (labeled) medullary descendants do not. In addition, parenteral administration of hydrocortisone at the time of surface labeling results in the absence of the appearance of labeled medullary descendants. |
| publisher |
The Rockefeller University Press |
| publishDate |
1973 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139480/ |
| _version_ |
1611421765303533568 |