DELETION OF HAPTEN-BINDING CELLS BY A HIGHLY RADIOACTIVE 125I CONJUGATE

Exposure of normal mouse spleen cells in vitro to highly 125I-labeled dinitrophenyl (DNP)-protein carrier conjugates specifically inactivated cells able to mount an immune response to that hapten after in vivo challenge. The deletion was hapten specific and independent of the radioactive carrier to...

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Bibliographic Details
Main Authors: Golan, Dov Theo, Borel, Yves
Format: Online
Language:English
Published: The Rockefeller University Press 1972
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139210/