MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE

Enhanced resistance against experimental tuberculosis was acquired by albino mice after peritoneal vaccination with living BCG. Prolongation of life was used as a measure of resistance against massive intravenous challenge infection. The average degree of prolongation of life was found to be direct...

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Main Authors:	Costello, Richard, Izumi, Takateru
Format:	Online
Language:	English
Published:	The Rockefeller University Press 1971
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138908/

id	pubmed-2138908
recordtype	oai_dc
spelling	pubmed-21389082008-04-17 MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE Costello, Richard Izumi, Takateru Article Enhanced resistance against experimental tuberculosis was acquired by albino mice after peritoneal vaccination with living BCG. Prolongation of life was used as a measure of resistance against massive intravenous challenge infection. The average degree of prolongation of life was found to be directly related to the size of the vaccinating dose. The ultimate numbers of BCG bacilli recovered from the animal's organs were also directly related to the quantity of vaccine initially administered. It appears therefore that the relative degree of antitubercular resistance achieved by immunized mice is closely related to the vaccinal population present in the animal's organs. The Rockefeller University Press 1971-01-31 /pmc/articles/PMC2138908/ /pubmed/5133864 Text en Copyright © 1971 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Costello, Richard Izumi, Takateru
spellingShingle	Costello, Richard Izumi, Takateru MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE
author_facet	Costello, Richard Izumi, Takateru
author_sort	Costello, Richard
title	MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE
title_short	MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE
title_full	MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE
title_fullStr	MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE
title_full_unstemmed	MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE
title_sort	measurement of resistance to experimental tuberculosis in albino mice : the immune phase
description	Enhanced resistance against experimental tuberculosis was acquired by albino mice after peritoneal vaccination with living BCG. Prolongation of life was used as a measure of resistance against massive intravenous challenge infection. The average degree of prolongation of life was found to be directly related to the size of the vaccinating dose. The ultimate numbers of BCG bacilli recovered from the animal's organs were also directly related to the quantity of vaccine initially administered. It appears therefore that the relative degree of antitubercular resistance achieved by immunized mice is closely related to the vaccinal population present in the animal's organs.
publisher	The Rockefeller University Press
publishDate	1971
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138908/
_version_	1611421429659598848

MEASUREMENT OF RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN ALBINO MICE : THE IMMUNE PHASE

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