IN VITRO-INITIATED SECONDARY ANTI-HAPTEN RESPONSE : II. INCREASING CELL AVIDITY FOR ANTIGEN

Decreasing antigen in vivo may preferentially stimulate cells with the potential for synthesis of high-affinity antibody through activation of surface receptors with similarly high affinity. This selection should result in cells with increased sensitivity to lower antigen concentrations, cells with...

Full description

Bibliographic Details
Main Authors: Bullock, Wesley W., Rittenberg, Marvin B.
Format: Online
Language:English
Published: The Rockefeller University Press 1970
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138869/