HAPTEN-CARRIER RELATIONSHIPS OF ISOANTIGENS : A MODEL FOR IMMUNOLOGICAL MATURATION BASED ON THE CONVERSION OF HAPTENS TO CARRIERS BY ANTIBODY

In chickens, erythrocyte isoantigens have hapten-carrier relationships. Specific anticarrier antibody depresses the immune response to the carrier and enhances the immune response to the hapten. Antigenic determinants of "haptenic" isoantigens behave as carriers if they are coated with sp...

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Bibliographic Details
Main Authors: McBride, Raymond A., Schierman, Louis W.
Format: Online
Language:English
Published: The Rockefeller University Press 1970
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138793/