RECOMBINATION OF ANTIBODY POLYPEPTIDE CHAINS IN THE PRESENCE OF ANTIGEN

Conditions were developed by which the separated H and L chains of gamma2 globulins recombined to form four-chained molecules in good yields. In the absence of antigen, anti-2,4-dinitrophenyl (anti-DNP) H chains randomly reassociated with a mixture of antibody and non-specific gamma2 globulin L cha...

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Bibliographic Details
Main Authors: Metzger, Henry, Mannik, Mart
Format: Online
Language:English
Published: The Rockefeller University Press 1964
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137869/