E1B 19K Inhibits Fas-mediated Apoptosis through FADD-dependent Sequestration of FLICE

E1B 19K, the adenovirus Bcl-2 homologue, is a potent inhibitor of apoptosis induced by various stimuli including Fas and tumor necrosis factor-α. Fas and TNFR-1 belong to a family of cytokine-activated receptors that share key components in their signaling pathways, Fas-associating protein with deat...

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Bibliographic Details
Main Authors: Perez, Denise, White, Eileen
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137191/