Death-effector Filaments: Novel Cytoplasmic Structures that Recruit Caspases and Trigger Apoptosis

The death-effector domain (DED) is a critical protein interaction domain that recruits caspases into complexes with members of the TNF-receptor superfamily. Apoptosis can also be induced by expressing certain DED-containing proteins without surface receptor cross-linking. Using Green Fluorescent Pro...

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Bibliographic Details
Main Authors: Siegel, Richard M., Martin, David A., Zheng, Lixin, Ng, Samuel Y., Bertin, John, Cohen, Jeffrey, Lenardo, Michael J.
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137190/