THE REMOVAL OF CARTILAGE MATRIX, IN VIVO, BY PAPAIN : IDENTIFICATION OF CRYSTALLINE PAPAIN PROTEASE AS THE CAUSE OF THE PHENOMENON
The intravenous injection of crystalline papain into young rabbits results in depletion of cartilage matrix throughout the body, with loss of rigidity and collapse of the ears, provided the enzyme is inactivated by oxidation or sulfhydryl blocking agents prior to administration. Cysteine-activated...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1958
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136872/ |