THE REMOVAL OF CARTILAGE MATRIX, IN VIVO, BY PAPAIN : IDENTIFICATION OF CRYSTALLINE PAPAIN PROTEASE AS THE CAUSE OF THE PHENOMENON

The intravenous injection of crystalline papain into young rabbits results in depletion of cartilage matrix throughout the body, with loss of rigidity and collapse of the ears, provided the enzyme is inactivated by oxidation or sulfhydryl blocking agents prior to administration. Cysteine-activated...

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Bibliographic Details
Main Authors: McCluskey, Robert T., Thomas, Lewis
Format: Online
Language:English
Published: The Rockefeller University Press 1958
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136872/