THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS

In experiments in which guinea pigs were infected concurrently with the virus of lymphocytic choriomeningitis and the parasitic nematode, Trichinella spiralis, proof was obtained that trichinella larvae, after maturation in the muscles, had acquired the virus and were capable of transmitting it to...

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Main Authors:	Syverton, J. T., McCoy, O. R., Koomen, J.
Format:	Online
Language:	English
Published:	The Rockefeller University Press 1947
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135680/

id	pubmed-2135680
recordtype	oai_dc
spelling	pubmed-21356802008-04-18 THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS Syverton, J. T. McCoy, O. R. Koomen, J. Article In experiments in which guinea pigs were infected concurrently with the virus of lymphocytic choriomeningitis and the parasitic nematode, Trichinella spiralis, proof was obtained that trichinella larvae, after maturation in the muscles, had acquired the virus and were capable of transmitting it to new susceptible hosts. Transmission resulted both when living larvae were fed to normal guinea pigs and when triturated dead larvae were injected subcutaneously. Control experiments and other tests made plain that transmission of the virus was not due to mere adherence of it to the outer surface of the larvae but that these actually harbored it. The significance of these experiments in relation to natural transmission of the virus of lymphocytic choriomeningitis remains to be determined. The Rockefeller University Press 1947-05-31 /pmc/articles/PMC2135680/ /pubmed/19871648 Text en Copyright © Copyright, 1947, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Syverton, J. T. McCoy, O. R. Koomen, J.
spellingShingle	Syverton, J. T. McCoy, O. R. Koomen, J. THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS
author_facet	Syverton, J. T. McCoy, O. R. Koomen, J.
author_sort	Syverton, J. T.
title	THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS
title_short	THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS
title_full	THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS
title_fullStr	THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS
title_full_unstemmed	THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS
title_sort	transmission of the virus of lymphocytic choriomeningitis by trichinella spiralis
description	In experiments in which guinea pigs were infected concurrently with the virus of lymphocytic choriomeningitis and the parasitic nematode, Trichinella spiralis, proof was obtained that trichinella larvae, after maturation in the muscles, had acquired the virus and were capable of transmitting it to new susceptible hosts. Transmission resulted both when living larvae were fed to normal guinea pigs and when triturated dead larvae were injected subcutaneously. Control experiments and other tests made plain that transmission of the virus was not due to mere adherence of it to the outer surface of the larvae but that these actually harbored it. The significance of these experiments in relation to natural transmission of the virus of lymphocytic choriomeningitis remains to be determined.
publisher	The Rockefeller University Press
publishDate	1947
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135680/
_version_	1611419608124751872

THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS

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