PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA

Electrophoretic patterns of human and dog plasma are markedly altered by the extraction of a large part of the plasma lipids. Total electrophoretic areas, relative areas of individual electrophoretic components, and electrophoretic albumin: globulin ratios undergo change. For human plasma, such ext...

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Main Authors:	Zeldis, L. J., Alling, E. L., McCoord, A. B., Kulka, J. P.
Format:	Online
Language:	English
Published:	The Rockefeller University Press 1945
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135566/

id	pubmed-2135566
recordtype	oai_dc
spelling	pubmed-21355662008-04-18 PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA Zeldis, L. J. Alling, E. L. McCoord, A. B. Kulka, J. P. Article Electrophoretic patterns of human and dog plasma are markedly altered by the extraction of a large part of the plasma lipids. Total electrophoretic areas, relative areas of individual electrophoretic components, and electrophoretic albumin: globulin ratios undergo change. For human plasma, such extractions confirm previous observations that a particularly rich lipid content characterizes beta globulin. Abnormally large beta peaks regularly occur in the presence of elevated plasma lipids. Marked increases in gamma globulin, however, are also found to be due in large part to elevated plasma lipid levels in certain abnormal human plasmas. The greatest relative amount of lipid in dog plasma, in contrast to human plasma, is associated not with the beta globulin, but with components usually designated as alpha globulins. Not only the areas, but the configuration and the number of alpha globulin peaks in dog plasma are altered by the extraction of plasma lipids. The results demonstrate that increased alpha globulin areas which occur in the plasma of hypoproteinemic dogs are due in large part to elevated plasma lipid levels. The Rockefeller University Press 1945-11-30 /pmc/articles/PMC2135566/ /pubmed/19871509 Text en Copyright © Copyright, 1945, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Zeldis, L. J. Alling, E. L. McCoord, A. B. Kulka, J. P.
spellingShingle	Zeldis, L. J. Alling, E. L. McCoord, A. B. Kulka, J. P. PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA
author_facet	Zeldis, L. J. Alling, E. L. McCoord, A. B. Kulka, J. P.
author_sort	Zeldis, L. J.
title	PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA
title_short	PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA
title_full	PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA
title_fullStr	PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA
title_full_unstemmed	PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA
title_sort	plasma protein metabolism—electrophoretic studies : the influence of plasma lipids on electrophoretic patterns of human and dog plasma
description	Electrophoretic patterns of human and dog plasma are markedly altered by the extraction of a large part of the plasma lipids. Total electrophoretic areas, relative areas of individual electrophoretic components, and electrophoretic albumin: globulin ratios undergo change. For human plasma, such extractions confirm previous observations that a particularly rich lipid content characterizes beta globulin. Abnormally large beta peaks regularly occur in the presence of elevated plasma lipids. Marked increases in gamma globulin, however, are also found to be due in large part to elevated plasma lipid levels in certain abnormal human plasmas. The greatest relative amount of lipid in dog plasma, in contrast to human plasma, is associated not with the beta globulin, but with components usually designated as alpha globulins. Not only the areas, but the configuration and the number of alpha globulin peaks in dog plasma are altered by the extraction of plasma lipids. The results demonstrate that increased alpha globulin areas which occur in the plasma of hypoproteinemic dogs are due in large part to elevated plasma lipid levels.
publisher	The Rockefeller University Press
publishDate	1945
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135566/
_version_	1611419542703046656

PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIES : THE INFLUENCE OF PLASMA LIPIDS ON ELECTROPHORETIC PATTERNS OF HUMAN AND DOG PLASMA

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