THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS

THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS

The V2 carcinoma—a transplanted rabbit cancer derived originally from a virus-induced papilloma and carrying in masked or altered form the virus primarily responsible for it—was propagated in five successive groups of animals all previously hyperimmunized against the papilloma virus. The cancer gre...

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Main Author: Kidd, John G.
Format: Online
Language:English
Published: The Rockefeller University Press 1942
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135214/
id pubmed-2135214
recordtype oai_dc
spelling pubmed-21352142008-04-18 THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS Kidd, John G. Article The V2 carcinoma—a transplanted rabbit cancer derived originally from a virus-induced papilloma and carrying in masked or altered form the virus primarily responsible for it—was propagated in five successive groups of animals all previously hyperimmunized against the papilloma virus. The cancer grew as well in the hyperimmunized hosts as in normal animals implanted during the same months; and serological tests, made when the tumor was eventually returned to ordinary hosts, proved that the virus was still associated with the carcinoma cells: it had increased to the usual extent as the tumor grew in the hyperimmune animals. The continued increase of the neoplastic virus during propagation of the V2 carcinoma in hyperimmunized hosts contrasts sharply with the elimination of certain extraneous passenger viruses when the tumors they ride upon are grown in hosts previously immunized against them. The facts as a whole would seem to warrant a distinction between the enduring partnership of a neoplastic virus and carcinoma cells on the one hand and the casual association of passenger viruses with tumor cells on the other. The Rockefeller University Press 1942-01-01 /pmc/articles/PMC2135214/ /pubmed/19871169 Text en Copyright © Copyright, 1942, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Kidd, John G.
spellingShingle Kidd, John G.
THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS
author_facet Kidd, John G.
author_sort Kidd, John G.
title THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS
title_short THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS
title_full THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS
title_fullStr THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS
title_full_unstemmed THE ENDURING PARTNERSHIP OF A NEOPLASTIC VIRUS AND CARCINOMA CELLS : CONTINUED INCREASE OF VIRUS IN THE V2 CARCINOMA DURING PROPAGATION IN VIRUS-IMMUNE HOSTS
title_sort enduring partnership of a neoplastic virus and carcinoma cells : continued increase of virus in the v2 carcinoma during propagation in virus-immune hosts
description The V2 carcinoma—a transplanted rabbit cancer derived originally from a virus-induced papilloma and carrying in masked or altered form the virus primarily responsible for it—was propagated in five successive groups of animals all previously hyperimmunized against the papilloma virus. The cancer grew as well in the hyperimmunized hosts as in normal animals implanted during the same months; and serological tests, made when the tumor was eventually returned to ordinary hosts, proved that the virus was still associated with the carcinoma cells: it had increased to the usual extent as the tumor grew in the hyperimmune animals. The continued increase of the neoplastic virus during propagation of the V2 carcinoma in hyperimmunized hosts contrasts sharply with the elimination of certain extraneous passenger viruses when the tumors they ride upon are grown in hosts previously immunized against them. The facts as a whole would seem to warrant a distinction between the enduring partnership of a neoplastic virus and carcinoma cells on the one hand and the casual association of passenger viruses with tumor cells on the other.
publisher The Rockefeller University Press
publishDate 1942
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135214/
_version_ 1611419338246455296

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