IMMUNIZATION OF GUINEA PIGS WITH A MODIFIED STRAIN OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS

A strain of choriomeningitis virus which was highly virulent for guinea pigs, as isolated from a naturally infected white mouse, has been markedly attenuated for guinea pigs by serial intracerebral passage through white mice. The change of virulence occurred before the 8th serial passage. The modif...

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Bibliographic Details
Main Author: Traub, Erich
Format: Online
Language:English
Published: The Rockefeller University Press 1937
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133621/