Adducin Is an In Vivo Substrate for Protein Kinase C: Phosphorylation in the MARCKS-related Domain Inhibits Activity in Promoting Spectrin–Actin Complexes and Occurs in Many Cells, Including Dendritic Spines of Neurons
Adducin is a heteromeric protein with subunits containing a COOH-terminal myristoylated alanine-rich C kinase substrate (MARCKS)-related domain that caps and preferentially recruits spectrin to the fast-growing ends of actin filaments. The basic MARCKS-related domain, present in α, β, and γ adducin...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1998
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133059/ |