The Nonreceptor Protein Tyrosine Phosphatase PTP1B Binds to the Cytoplasmic Domain of N-Cadherin and Regulates the Cadherin–Actin Linkage
Cadherin-mediated adhesion depends on the association of its cytoplasmic domain with the actin-containing cytoskeleton. This interaction is mediated by a group of cytoplasmic proteins: α-and β- or γ- catenin. Phosphorylation of β-catenin on tyrosine residues plays a role in controlling this associat...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1998
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132848/ |