Differential Stimulation of the Na+/H+ Exchanger Determines Chloroquine Uptake in Plasmodium falciparum

Here we describe the identification and characterization of a physiological marker that is associated with the chloroquine-resistant (CQR) phenotype in the human malarial parasite Plasmodium falciparum. Single cell in vivo pH measurements revealed that CQR parasites consistently have an elevated cyt...

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Bibliographic Details
Main Authors: Wünsch, Stefan, Sanchez, Cecilia P., Gekle, Michael, Große-Wortmann, Lars, Wiesner, Jochen, Lanzer, Michael
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132566/