Calcium Release at Fertilization in Starfish Eggs Is Mediated by Phospholipase Cγ

Although inositol trisphosphate (IP3) functions in releasing Ca2+ in eggs at fertilization, it is not known how fertilization activates the phospholipase C that produces IP3. To distinguish between a role for PLCγ, which is activated when its two src homology-2 (SH2) domains bind to an activated tyr...

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Bibliographic Details
Main Authors: Carroll, David J., Ramarao, Chodavarapu S., Mehlmann, Lisa M., Roche, Serge, Terasaki, Mark, Jaffe, Laurinda A.
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132564/