DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING

A method is described for estimating the volume of air in the lungs by the familiar principle of mixing this air with a measured volume of oxygen, and determining the extent to which the nitrogen of the pulmonary air is diluted. By employing a scrubber to remove carbon dioxide, and by measuring the...

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Main Authors:	Sendroy, Julius, Hiller, Alma, Van Slyke, Donald D.
Format:	Online
Language:	English
Published:	The Rockefeller University Press 1932
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132104/

id	pubmed-2132104
recordtype	oai_dc
spelling	pubmed-21321042008-04-18 DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING Sendroy, Julius Hiller, Alma Van Slyke, Donald D. Article A method is described for estimating the volume of air in the lungs by the familiar principle of mixing this air with a measured volume of oxygen, and determining the extent to which the nitrogen of the pulmonary air is diluted. By employing a scrubber to remove carbon dioxide, and by measuring the volume of gas in the extrapulmonary part of the system at the end instead of the beginning of the respiratory period, it is possible to prolong the period to as many minutes as are necessary for complete mixture of the gases, and thereby to carry out the estimation without forced breathing. The determination can be carried out with the Roth-Benedict or Krogh spirometer, or, more economically, with the simple spirometer, shown in Fig. 1, assembled from ordinary laboratory equipment. The method gives the same results as the hydrogen method of Van Slyke and Binger (3), and obviates the use and analysis of hydrogen. The relative advantages of the two methods are discussed above. Dr. Ronald V. Christie has informed us that he has encountered considerable differences in the N2 content of the pulmonary air of different individuals. A gain in accuracy would therefore be made if this value were determined for each subject, and substituted for 79.1 in the calculation formulae. The Rockefeller University Press 1932-02-29 /pmc/articles/PMC2132104/ /pubmed/19869996 Text en Copyright © Copyright, 1932, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Sendroy, Julius Hiller, Alma Van Slyke, Donald D.
spellingShingle	Sendroy, Julius Hiller, Alma Van Slyke, Donald D. DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING
author_facet	Sendroy, Julius Hiller, Alma Van Slyke, Donald D.
author_sort	Sendroy, Julius
title	DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING
title_short	DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING
title_full	DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING
title_fullStr	DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING
title_full_unstemmed	DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING
title_sort	determination of lung volume by respiration of oxygen without forced breathing
description	A method is described for estimating the volume of air in the lungs by the familiar principle of mixing this air with a measured volume of oxygen, and determining the extent to which the nitrogen of the pulmonary air is diluted. By employing a scrubber to remove carbon dioxide, and by measuring the volume of gas in the extrapulmonary part of the system at the end instead of the beginning of the respiratory period, it is possible to prolong the period to as many minutes as are necessary for complete mixture of the gases, and thereby to carry out the estimation without forced breathing. The determination can be carried out with the Roth-Benedict or Krogh spirometer, or, more economically, with the simple spirometer, shown in Fig. 1, assembled from ordinary laboratory equipment. The method gives the same results as the hydrogen method of Van Slyke and Binger (3), and obviates the use and analysis of hydrogen. The relative advantages of the two methods are discussed above. Dr. Ronald V. Christie has informed us that he has encountered considerable differences in the N2 content of the pulmonary air of different individuals. A gain in accuracy would therefore be made if this value were determined for each subject, and substituted for 79.1 in the calculation formulae.
publisher	The Rockefeller University Press
publishDate	1932
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132104/
_version_	1611418148909613056

DETERMINATION OF LUNG VOLUME BY RESPIRATION OF OXYGEN WITHOUT FORCED BREATHING

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