STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS.

A study has been made of the biological effect of a small dose of soft x-rays given off by a special water-cooled tube with a window of thin glass, operated at ½ inch spark-gap and 11 milliamperes. Mice exposed for 1 minute show 2 days later in the blood an increase in the number of lymphocytes and...

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Main Authors: Nakahara, Waro, Murphy, James B.
Format: Online
Language:English
Published: The Rockefeller University Press 1922
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128123/
id pubmed-2128123
recordtype oai_dc
spelling pubmed-21281232008-04-18 STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS. Nakahara, Waro Murphy, James B. Article A study has been made of the biological effect of a small dose of soft x-rays given off by a special water-cooled tube with a window of thin glass, operated at ½ inch spark-gap and 11 milliamperes. Mice exposed for 1 minute show 2 days later in the blood an increase in the number of lymphocytes and in the lymphoid organs an increased number of mitotic figures. There occurs also a marked dilatation of the vessels of the suprarenals, particularly between the cortex and medulla. The latter condition did not appear until after 24 hours and was still present 14 days after the treatment. No change was detected in other organs. Mice treated in this way showed a high degree of resistance to cancer transplants. The amount of resistance varied with the time of the inoculation after the treatment. The resistance was not increased before 3 days after and was at its highest point 10 days after the treatment. The Rockefeller University Press 1922-03-31 /pmc/articles/PMC2128123/ /pubmed/19868621 Text en Copyright © Copyright, 1922, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Nakahara, Waro
Murphy, James B.
spellingShingle Nakahara, Waro
Murphy, James B.
STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS.
author_facet Nakahara, Waro
Murphy, James B.
author_sort Nakahara, Waro
title STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS.
title_short STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS.
title_full STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS.
title_fullStr STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS.
title_full_unstemmed STUDIES ON X-RAY EFFECTS : X. THE BIOLOGICAL ACTION OF SMALL DOSES OF LOW FREQUENCY X-RAYS.
title_sort studies on x-ray effects : x. the biological action of small doses of low frequency x-rays.
description A study has been made of the biological effect of a small dose of soft x-rays given off by a special water-cooled tube with a window of thin glass, operated at ½ inch spark-gap and 11 milliamperes. Mice exposed for 1 minute show 2 days later in the blood an increase in the number of lymphocytes and in the lymphoid organs an increased number of mitotic figures. There occurs also a marked dilatation of the vessels of the suprarenals, particularly between the cortex and medulla. The latter condition did not appear until after 24 hours and was still present 14 days after the treatment. No change was detected in other organs. Mice treated in this way showed a high degree of resistance to cancer transplants. The amount of resistance varied with the time of the inoculation after the treatment. The resistance was not increased before 3 days after and was at its highest point 10 days after the treatment.
publisher The Rockefeller University Press
publishDate 1922
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128123/
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