Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions

Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions

RNA-mediated interference (RNAi) is a method to inhibit gene function by introduction of double-stranded RNA (dsRNA). Recently, an RNAi library was constructed that consists of bacterial clones expressing dsRNA, corresponding to nearly 90% of the 19,427 predicted genes of C. elegans. Feeding of this...

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Bibliographic Details
Main Authors: Simmer, Femke, Moorman, Celine, van der Linden, Alexander M, Kuijk, Ewart, van den Berghe, Peter V.E, Kamath, Ravi S, Fraser, Andrew G, Ahringer, Julie, Plasterk, Ronald H. A
Format: Online
Language:English
Published: Public Library of Science 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212692/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212692/

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