NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis

NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis

Primary biliary cirrhosis (PBC) is an autoimmune disease with a strong genetic component characterized by biliary ductular inflammation with eventual liver cirrhosis. The serologic hallmark of PBC is antimitochondrial antibodies that react with the pyruvate dehydrogenase complex, targeting the inner...

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Bibliographic Details
Main Authors: Irie, Junichiro, Wu, Yuehong, Wicker, Linda S., Rainbow, Daniel, Nalesnik, Michael A., Hirsch, Raphael, Peterson, Laurence B., Leung, Patrick S.C., Cheng, Chunmei, Mackay, Ian R., Gershwin, M. Eric, Ridgway, William M.
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121204/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121204/

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