Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeast
The spindle assembly checkpoint is the mechanism or set of mechanisms that prevents cells with defects in chromosome alignment or spindle assembly from passing through mitosis. We have investigated the effects of mini-chromosomes on this checkpoint in budding yeast by performing pedigree analysis. T...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1996
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120768/ |