Constitutive expression of calreticulin in osteoblasts inhibits mineralization

Recent studies have shown that the multifunctional protein calreticulin can localize to the cell nucleus and regulate gene transcription via its ability to bind a protein motif in the DNA-binding domain of nuclear hormone receptors. A number of known modulators of bone cell function, including vitam...

Full description

Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1995
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120639/