NAC covers ribosome-associated nascent chains thereby forming a protective environment for regions of nascent chains just emerging from the peptidyl transferase center
We demonstrate that nascent polypeptide-associated complex (NAC) is one of the first cytosolic factors that newly synthesized nascent chains encounter. When NAC is present, nascent chains are segregated from the cytosol until approximately 30 amino acids in length, a finding consistent with the well...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1995
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120527/ |