Inhibition of desmin expression blocks myoblast fusion and interferes with the myogenic regulators MyoD and myogenin
The muscle-specific intermediate filament protein, desmin, is one of the earliest myogenic markers whose functional role during myogenic commitment and differentiation is unknown. Sequence comparison of the presently isolated and fully characterized mouse desmin cDNA clones revealed a single domain...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1994
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119944/ |