Thrombin adhesive properties: induction by plasmin and heparan sulfate

We have previously demonstrated that chemically modified thrombin preparations induce endothelial cell (EC) adhesion, spreading and cytoskeletal reorganization via an Arg-Gly-Asp (RGD) sequence and the alpha v beta 3 integrin. Native thrombin, however, did not exhibit adhesive properties, consistent...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1993
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119867/