Biased distribution of recombination sites within S regions upon immunoglobulin class switch recombination induced by transforming growth factor beta and lipopolysaccharide

We have characterized extrachromosomal circular DNAs from adult mouse spleen cells that were induced to switch to immunoglobulin A (IgA) with bacterial lipopolysaccharide (LPS) and transforming growth factor beta (TGF-beta), and identified breakpoints of S mu/S gamma 3, S mu/S gamma 2, S mu/S alpha,...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1992
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119254/